Mass Spectrometry in Cancer Research

【编者】：John Roboz

【出版】：2002年3月25日CRC Press出版

【ISBN】：084930167X。

【简介】：目前癌研究成为一种多学科的课题。其中复杂的结构和治疗问题需要采用能够互相促进、协作方法，如生物化学操作、色谱或电泳（Electrophoretic） 分离及质谱法。

        本书介绍了质谱仪的工作原理；简要介绍在生物、药理学中的应用，综合了2001年6月以来1800篇参考文献；列举了大量的目前广泛应用的方法和技术，介绍了这些技术主要应用于以下领域： 1）职业和环境致癌物； 2）抗神经塑料（Antineoplastic）和化学预防（Chemopreventive）试剂；3）相关的蛋白质、液体、核酸和共轭糖（Glycoconjugates）；概述了生物学家和内科医生所应用的相关仪器及方法，为质谱工作者简要回顾了癌生物学和医学的一些重要概念。

        本书为质谱工作者提供生物、医学、药物学或环境科学研究方面的参考，适用于从事理论医学的内科医生和理论/工业研究的管理者阅读参考。

Plasma Source Mass Spectrometry: The New Millennium 2001

【Editor】:J G Holland and S D Tanner

【Introduction】：The understanding of the principles of ICP-MS and its application as an analytical technique is continually evolving and this book provides a unique snapshot of the current state-of-the-art. Plasma Source Mass Spectrometry: The New Millennium covers a diverse range of topics including the fate of the sample as it passes through the sample introduction system, chemical resolution using reaction and collision cells, various methods of mass analysis, approaches to account for spectral interferences, hyphenation methods to enable speciation, and the results of analyses ranging from natural waters and archaeological isotope ratios to organometallic speciation in biological materials.   Describing explicitly the analytical methods that deal with current analytical challenges, and offering a current perspective on elemental analysis by plasma source mass spectrometry that is not to be found elsewhere, this book will be welcomed by both academics and industrialists as containing the most up-to-date information available on this burgeoning topic.

Mass Spectrometry of Natural Substances in Food

【Author】: F Mellon, R Self, J R Startin

【Introduction】:Introducing the principles, practice and applications of mass spectrometric techniques in the study of natural substances in foods, this book conveys the depth and breadth of modern mass spectrometry in relation to food analysis. It covers traditional techniques such as electron and chemical ionization and newer soft ionization techniques such as matrix-assisted laser desorption ionization and electrospray. All of these techniques are especially relevant in food quality and safety studies and in biopolymer analysis. The ability to analyze biopolymers by mass spectrometry is having a major impact on the study of food structure components, food proteins, food pathogens and food components produced from genetically modified organisms. The principles and practice of mass spectrometry are covered in the early chapters and are followed by applications in flavor analysis and the determination of non-nutrient, biologically-active, natural substances in foods. The analysis and metabolic studies of amino acids, peptides, proteins, lipids, sugars, carbohydrates and vitamins is also discussed, with separate chapters on mineral and micronutrient metabolism and techniques of pyrolysis mass spectrometry. Mass Spectrometry of Natural Substances in Food will be a valuable resource for food scientists, food analysts and others working in food research, nutrition and safety.

Mass Spectrometry Basics

【Introduction】: Offers a detailed overview of theory and instrumentation; Includes over 300 figures and

tables;Contains over 40 quick guides that serve as a brief overview of the key information in each chapter ；Provides a glossary of terms that explains the acronyms used in mass spectrometry. Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. Additionally, the authors have included an extensive reference section and a quick guide to each chapter that offers immediate access to key information. This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. It also serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology.

         Practical Aspects of Ion Trap MS: Chemical, Environmental, and Biomedical Applications, Volume III

【Introduction】:Introduction to ion trap theory, design, and operation; Examination of important areas of

ion trap mass spectro-metric activity ；Several chapters dedicated to the use of ion trap mass spectrometry in environmental analysis By delivering concentrated information in three different volumes, the editors of the Practical Aspects of Ion Trap Mass Spectrometry mini-series present in-depth reviews on mainstream developments in each active and popular area. Contributing authors provide concise reports illustrating successful approaches to difficult analytical problems across the basic scientific disciplines. Volume three, Chemical, Environmental, and Biomedical Applications, presents a coherent picture of research and applications in the ion trapping field. It examines tandem mass spectrometry, the principal mode of ion trap operation, where one stage of mass selectivity follows another in the same region of space. This volume discusses the fundamentals of ion trap theory, design, and operation; practical ion trap technology; applications involving small molecules; and the environmental and biomedical applications.

Mass Spectrometry of Polymers

【Introduction】: Bridges the gap between traditional polymer analysis methods and the emerging field of

polymer mass determine exact oligomer masses; Describes the use of mass spectrometry to determine absolute molecular weight distributions; Describes methods to determine the chemical structure of polymers, including monomer types, end groups, and microstructure; Discusses the characterization of additives, impurities, and degradation products in polymeric materials; Includes the most recent advances in matrix-assisted laser desorption/ionization mass spectrometry, already a standard tool for polymer analysis ；Discusses time-of-flight secondary ion mass spectrometry, which is revolutionizing bulk polymer as well as surface characterization Mass Spectrometry (MS) has rapidly become an indispensable tool in polymer analysis, and modern MS today complements in many ways the structural data provided by Nuclear Magnetic Resonance (NMR) and Infrared (IR) methods. Recent advances have sparked a growing interest in this field and established a need for a summary of progress made and results achieved. Mass Spectrometry of Polymers effectively fills this need. The discussion begins by introducing MS in detail, providing a historical perspective and a review of modern instrumentation and methods. The text then focuses on mathematical concepts and practical algorithms used in some of the major quantitative polymer applications of MS, providing a skillful prologue to polymer characterization techniques. Detailed chapters follow, describing the most relevant applications of MS to the analysis of polymers and the techniques currently employed. Authored by internationally recognized experts from academia and industry, Mass Spectrometry of Polymers is the only state-of-the-art work available that deals systematically with this rapidly emerging discipline, and will be useful to both novices and experienced practitioners in polymer MS.

Inductively Coupled Plasma Spectrometry and Its Applications

【List Price】: $149.95Cat.

【ISBN】: 0849397391Publication Date: 3/23/1999Number of Pages: 384

【Introduction】: Provides an introduction to ICP spectrometry, discussing its historical development, detection limits, precision and dynamic range, and multielement capability and selectivity； Describes environmental applications of plasma spectrometry, including spectroscopic interferences, air samples, and water samples; Examines trace element analysis as well as the determination of rare earth elements concerning the application of plasma spectrometry to earth science； Explains total analyte determinations in food and speciation studies in applying plasma spectrometry to food science ICP Spectrometry and Its Applications provides an up-to-date resource for researchers and professionals in academia and industry. Directed at analytical chemists, environmental scientists, geochemists, and earth scientists, the book outlines ICP-MS as well as applications of plasma spectrometry in environmental analysis, earth science, and food science.

GC-MS Guide to Ignitable Liquids

【Introduction】:Provides more than 100 different ignitable liquid formulations - both total ion

chromatograms and extracted ion chromatograms (mass chromatograms) ； Contains data not previously available in a single resource, including previously unpublished data on new products The rapidly increasing number of different ignitable liquid formulations available today poses a new challenge to fire debris analysts and other forensic chemistry specialists - that of accurately identifying and classifying ignitable liquids with unfamiliar chromatographic patterns. GC-MS Guide to Ignitable Liquids addresses that challenge with a selection of more than 100 different ignitable liquid formulations designed to supplement the laboratory's standard collection. Both total ion chromatograms and extracted ion chromatograms (mass chromatograms) are included. Written by authors who are also experienced forensic chemists, this complete reference is the only single source of information on ignitable liquids - a must for students of fire science, forensic chemists, and anyone conducting fire debris analysis.

HPLC: Practical and Industrial Applications, Second Edition

【Author】:Joel K Swadesh Seraf Therapeutics, Inc., Albuquerque, New Mexico, USA

【Introduction】:Presents highly conceptual information in plain language, making it accessible to students and easy to read for experienced scientists； Includes a comprehensive review of HPLC literature, eliminating the need for multiple references; Provides extensive indexing and a careful structure to facilitate rapid answers to urgent problems ；Integrates important non-technical issues with the realities of the workplace, including discussion of a range of topics, from management theory to regulatory considerations and ethics New in the Second Edition: Updates of all major topics highlighting recent literature and new developments; Expanded discussion of mass spectroscopy, electrophoretic separations, and ultra-micro separations； Further discussion on the nature and future of industrial development Product specifications, regulatory constraints, and tight production schedules impose considerable pressures on separation scientists in industry. The first edition of HPLC: Practical and Industrial Applications helped eliminate the need for extensive library or laboratory research when confronting a problem, an unfamiliar technique, or work in a new area. Its plain language, comprehensive coverage of separation topics, and practical organization made it an accessible and convenient reference manual for anyone working in or just entering the field. Since its publication in 1997, however, much has changed. The areas of mass spectroscopy, electrophoretic separations, and ultra-micro separations have blossomed, focus on quality control has intensified, and the literature has grown significantly. The Second Edition incorporates all of these changes and more. It is now fully current, with chapter supplements that include updated references and discussions of techniques. This book examines analytical HPLC as it is actually used in industry. Whether you are just entering industry, switching from one industry to another, or simply enjoy understanding how things are made, HPLC: Practical and Industrial Applications will help you solve problems and get up to speed in new areas quickly, comfortably, and with a genuine sense of mastery.