同位素 ›› 2020, Vol. 33 ›› Issue (5): 279-285.DOI: 10.7538/tws.2020.33.05.0279

• 稳定同位素技术在食品安全检测中的应用专辑 • 上一篇    下一篇

邻苯二甲酸酯类标准物质在婴幼儿乳粉塑化剂检测中的应用研究

孙雯;李杰;杜晓宁;徐仲杰;潘洁;尤雅芳;李美华   

  1. 上海化工研究院有限公司,上海200062;上海计量测试技术研究院,上海201203
  • 出版日期:2020-10-20 发布日期:2020-10-28

Study on the Application of Phthalate Esters in The Detection of Plasticizer in Infant Milk Powder

SUN Wen;LI Jie;DU Xiaoning;XU Zhongjie;PAN Jie;YOU Yafang;LI Meihua   

  1. Shanghai Research Institute of Chemical Industry CO., LTD., Shanghai 200062, China; National Isotope Engineering Technology Research Center-Shanghai Sub-Center, Shanghai 201203, China
  • Online:2020-10-20 Published:2020-10-28

摘要:

采用自行研制的6种氘标记邻苯二甲酸酯做内标,对婴幼儿乳粉中16种邻苯二甲酸酯进行测定。乳粉中加入一定量氘标记邻苯二甲酸酯后采用超纯水溶解,利用正己烷进行提取,采用气相色谱-质谱联用仪在选择离子模式下进行分析,内标法定量。16种邻苯二甲酸酯在0.02 μg/mL~1.0 μg/mL范围内线性关系良好,相关系数均大于0.999。基质空白加标在0.05 μg/mL~1.0 μg/mL范围内时回收率为90.8%~103.6%,相对偏差为0.51%~3.75%。同位素内标的使用消除了基质效应对检测产生的影响,提高了检测方法的回收率,有效避免痕量检测中假阳性现象的发生。

关键词: 氘标记邻苯二甲酸酯, 婴幼儿乳粉, 塑化剂, 检测

Abstract:

Infant milk powder is the main dietary nutrition source for infants except breast milk, and its product quality directly affects infant development. Sixteen phthalates in infant milk powder were determined by using six deuterium labeled phthalates as internal standard. After a certain amount of deuterium was added into the milk powder, phthalate was dissolved in ultra-pure water, extracted with hexane, analyzed with gas chromatography-mass spectrometry and determined with internal standard method. The linear relationship of 16 phthalates was good in the range of 0.02 μg/mL to 1.0 μg/mL, and the correlation coefficients were all greater than 0.999. The recovery was 90.8%-103.6% in the range of 0.05 μg/mL-1.0 μg/mL and the relative deviation was 0.51%-3.75%. The effect of matrix effect on detection is eliminated and the recovery of detection method is improved.

Key words: deuterium labeled phthalate, infant milk powder, plasticizer, detection