同位素 ›› 2018, Vol. 31 ›› Issue (2): 114-122.DOI: 10.7538/tws.2017.youxian.025

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心血管疾病PET显像剂研究进展

马慧1;梁宏1;徐万帮2;唐刚华1   

  1. 1.中山大学附属第一医院 广东省医用放射性药物转化应用工程技术研究中心 核医学科,广东 广州510080;2.广东省药品检验所,广东 广州510180
  • 出版日期:2018-04-20 发布日期:2018-04-17

Progress of PET Imaging Agents for Cardiovascular Diseases

MA Hui1;LIANG Hong1;XU Wan-bang2;TANG Gang-hua1   

  1. 1.Guangdong Engineering Research Center for Translational Application of Medical Radiopharmaceuticals and Department of Nuclear Medicine, The First Affiliated Hospital of  Sun YatSen University, Guangzhou 510080, China; 2.Guangdong Institute of Drug Control, Guangzhou 510180, China
  • Online:2018-04-20 Published:2018-04-17

摘要:

正电子发射断层(PET)显像可用于监测非侵袭性心血管病变,有良好的临床应用前景。各种显像剂的转化应用使PET从分子水平上早期发现和评估心血管疾病,提高了心血管疾病早期诊断和疗效监测的灵敏度和特异性。本文介绍了用于心血管疾病的PET显像剂及其应用进展。

关键词: 心血管疾病, 正电子发射断层(PET), 放射性示踪剂

Abstract:

Positron emission tomography ( PET) imaging has successfully allowed the noninvasive detection of cardiovascular disease and shows good clinical application prospects. Development and translation application of various imaging agents furtherly enable PET imaging to be used for early detection and progression evaluation of cardiovascular diseases at molecular level, which can improve sensitivity and specificity of early diagnosis and monitoring of the diseases. This review mainly describes development and application progression of PET tracers for cardiovascular diseases imaging.

Key words: cardiovascular diseases, positron emission tomography, radioactive tracers