同位素 ›› 2002, Vol. 15 ›› Issue (3 ): 151-151 .DOI: 10.7538/tws.2002.15.03.0151

• 论文 • 上一篇    下一篇

~(99)Tc~m-HL91在体外乏氧心肌细胞中的动力学观察

作者   

  1. @侯妮$西安交通大学第一医院核医学科!陕西西安 710061 @邹保民$西安交通大学第一医院核医学科!陕西西安 710061 @胡国瑛$西安交通大学第一医院核医学科!陕西西安 710061 @刘巧芳$西安交通大学医学院核医学教研室!陕西西安 710061 @邓惠兴$西安交通大学第一医院核医学科!陕西西安 710061 @李杰$武警陕西总队医院外一科!陕西西安 710061
  • 收稿日期:2001-11-02 出版日期:2002-08-20 发布日期:2002-08-20

The Dynamic of Cardiac Myocyte Hypoxia Trapping ~(99)Tc~m-HL91

  1. HOU Ni1, ZOU Baomin1, HU Guoying1, LIU Qiaofang2, DENG Huixing1, LI Jie3(1. Department of Nuclear Medicine, the First Hospital of Xi'an Jiaotong University, Xi'an 710061, China;2. Nuclear Medicine Department of the Medical College of Xi'an Jiaotong University, Xi'an 710061, China;3. The First Surgery of Gerenal Hospital of Armed Police in Shanxi, Xi'an 710061, China)
  • Received:2001-11-02 Online:2002-08-20 Published:2002-08-20

摘要: 采用原代培养心肌细胞,观察其摄取与清除99Tcm-HL91的情况,并测定心肌细胞的活力。结果表明:乏氧组心肌细胞仍存活,其摄取99Tcm-HL91较正常组明显增高(P<0.05),清除相对缓慢,但尚无明显差异;180min时,乏氧组心肌细胞内99Tcm-HL91的存留量是正常组的3.0倍,可用于探测心肌细胞乏氧。

关键词: 99Tcm-HL91, 乏氧心肌细胞, 动力学

Abstract: The dynamics of 99TcmHL91 in myocardium cell primarily cultured are observed. The results show that hypoxic myocytes are still alive , the uptake of 99TcmHL91 is higher than the normal(P<0.05), the clearing is slower but there is no different statistically, the retention of viable hypoxic myocytes is 3 times as the normal at 180 min.

Key words: ~(99)Tc~m-HL91, cardiac myocyte hypoxia, dynamic

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